发明名称 |
Methods for the inhibition of neointima formation |
摘要 |
Restenosis is inhibited through local delivery of anti-restenotic agents including angiotensin converting enzyme inhibitors; nicotine receptor agonists, agents that increase concentrations of nitric oxide, anti-angiogenic agents, agonists of the TGF-beta receptor; death domain receptor ligands; and thrombin inhibitors. In one embodiment of the invention, the localized delivery is effected through the use of a stent modified for delivery of the agent at the site of injury from balloon angioplasty.
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申请公布号 |
US2002193336(A1) |
申请公布日期 |
2002.12.19 |
申请号 |
US20020101453 |
申请日期 |
2002.03.11 |
申请人 |
ELKINS CHRISTOPHER J.;DAKE MICHAEL D.;WAUGH JACOB M. |
发明人 |
ELKINS CHRISTOPHER J.;DAKE MICHAEL D.;WAUGH JACOB M. |
分类号 |
A61F2/00;A61F2/06;A61F2/90;A61L31/14;A61L31/16;(IPC1-7):A61K48/00;A61K31/474;A61M1/00;A61K33/00 |
主分类号 |
A61F2/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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