METHODS AND CELLS FOR DETECTING MODULATORS OF RGS PROTEINS

摘要

This application describes novel cells that respond to a pheromone comrising a heterologous nucleic acid encoding a reporter operably linked to a pheromone-responsive promoter. The cells may further comprises a heterologous nucleic acid encoding an RGS protein. Also described are methods involving the use of these cells for detecting the ability of a test sample to alter RGS protein-mediated reporter gene expression.