THE C. ALBICANS TEC1 GENE (CATEC1) AND THE CODED TEC1P PROTEIN

摘要

The invention relates to nucleotide sequences which code for proteins which modulate the virulence of pathogenic fungal strains, to vectors containing these sequences, to host cells having these nucleotide sequences or these vectors, to proteins which modulate the virulence of pathogenic fungal strains, especially the transcription factor CaTEC1 of Candida albicans, to inhibitors thereof, especially antibodies which target these virulence-modifying proteins, to methods for producing the proteins and inhibitors, to methods for the diagnosis and therapy of diseases which are associated with a Candida infection and to diagnostic and pharmaceutical compositions containing the nucleotide sequences, proteins, host cells and/or antibodies.