发明名称 CHEMOKIN REZEPTOR ANTAGONIST UND CYCLOSPORIN IN KOMBINATIONSTHERAPIE
摘要 The use of a chemokine receptor antagonist together with a cyclosporin to produce a pharmaceutical composition for treating or preventing rejection of transplanted organs, tissues or cells is herein disclosed. Said pharmaceutical compositions for the simultaneous, separate or sequential use of its active ingredients for the above specified therapy are also disclosed and claimed. In particular, the use of Met-RANTES together with cyclosporin A to produce a pharmaceutical composition for the treatment of renal allograft transplant rejection is experimentally shown.
申请公布号 DE69903964(D1) 申请公布日期 2002.12.19
申请号 DE1999603964 申请日期 1999.09.16
申请人 APPLIED RESEARCH SYSTEMS ARS HOLDING N.V., CURACAO 发明人 GRONE, HERMANN-JOSEPH;NELSON, J.;PROUDFOOT, AMANDA;WELLS, N.
分类号 A61K45/00;A61K;A61K38/00;A61K38/13;A61K38/19;A61P37/06;C07K14/52;(IPC1-7):A61K38/19 主分类号 A61K45/00
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