发明名称 HIV PROTEASE INHIBITORS, COMPOSITIONS CONTAINING THE SAME, THEIR PHARMACEUTICAL USES AND MATERIALS FOR THEIR SYNTHESIS
摘要 Compounds of formula (I) where the formula variables are as defined herein, are disclosed that advantageously inhibit or block the biological activity o f the HIV protease. Theses compounds, as well as pharmaceutical compositions containing these compounds, are useful for treating patients or hosts infect ed with the HIV virus. Intermediates and synthetic methods for preparing such compounds are also described.
申请公布号 CA2450269(A1) 申请公布日期 2002.12.19
申请号 CA20022450269 申请日期 2002.06.11
申请人 AGOURON PHARMACEUTICALS, INC 发明人 JEWELL, TANYA M.;BURKE, BENJAMIN J.;VARNEY, MICHAEL D.;TATLOCK, JOHN H.;REICH, SIEGFRIED H.;VIRGIL, SCOTT C.;MACHAK, JEFF;KUCERA, DAVID J.;BARVIAN, MARK;PRASAD JOSYULA VARA;MITCHELL, LENNERT J.;BOLTON, GARY;WORLAND, STEPHEN T.;MURPHY, SEAN T.;ALEXANDER, THERESE N.;MELNICK, MICHAEL;CANON-KOCH, STACIE S.;BOYER, FREDRICK E.;SKALITZKY, DONALD J.;HOLLER, TOD;LINTON, MARIA A.;WEBBER, STEPHEN E.
分类号 C07D277/04;A61K31/40;A61K31/401;A61K31/4025;A61K31/421;A61K31/422;A61K31/425;A61K31/426;A61K31/427;A61K31/428;A61K31/435;A61K31/439;A61K31/4439;A61K31/454;A61K31/4709;A61K31/472;A61K31/501;A61K31/5377;A61K31/541;A61K38/04;A61K45/00;A61P31/00;A61P31/12;A61P31/18;A61P37/02;A61P43/00;C07D207/09;C07D207/16;C07D207/24;C07D209/52;C07D213/38;C07D217/26;C07D231/12;C07D263/04;C07D263/06;C07D277/00;C07D277/06;C07D277/20;C07D277/28;C07D277/32;C07D277/38;C07D277/60;C07D295/13;C07D307/52;C07D403/12;C07D405/12;C07D409/12;C07D413/12;C07D417/12;C07D417/14;C07D471/08;C07K5/04;(IPC1-7):C07D277/06 主分类号 C07D277/04
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