| 摘要 |
<p>Novel compounds of formula (I) wherein R1 represents hydrogen; R2 represents hydroxy, fluoro or an oxo group;R3 represents hydrogen; R4 represents hydrogen; and pharmaceutically acceptable salts, solvates and the stereoisomers thereof, with the exception of the racemate of (3-amino-2-hydroxypropyl)sulphinic acid.The compounds are useful in therapy, especially for the treatment of reflux disease. The invention is also related to processes for their preparation, intermediates of said process and pharmaceutical compositions containing said therapeutically active compounds and to the use of said active compounds in therapy.</p> |
