| 发明名称 |
SULFONAMIDE LACTAM INHIBITORS OF FACTOR XA |
| 摘要 |
Sulfonamide lactams of the formula (I) wherein X, R<1>, R<2>, R<3>, R<4>, R<4a>, R<5>, R<5a>, R<6>, R<6a>, R<7> and R<8> are as described herein, are provided which inhibitors of Factor Xa and are useful as anticoagulants in the treatment of cardiovascular diseases associated with thromboses. |
| 申请公布号 |
WO02060894(A3) |
申请公布日期 |
2002.12.19 |
| 申请号 |
WO2002US02542 |
申请日期 |
2002.01.28 |
| 申请人 |
BRISTOL-MYERS SQUIBB COMPANY;O'CONNOR, STEPHEN, P.;LAWRENCE, R., MICHAEL;SHI, YAN;STEIN, PHILIP, P. |
发明人 |
O'CONNOR, STEPHEN, P.;LAWRENCE, R., MICHAEL;SHI, YAN;STEIN, PHILIP, P. |
| 分类号 |
C07D487/08;A61K31/37;A61K31/42;A61K31/4365;A61K31/439;A61K31/444;A61K31/445;A61K31/454;A61K31/4545;A61K31/4709;A61K31/4725;A61K31/496;A61K31/4995;A61K31/506;A61K31/517;A61K31/519;A61K31/5377;A61K31/5386;A61K31/541;A61K31/545;A61K31/55;A61K31/616;A61K38/43;A61K38/46;A61K45/00;A61P1/04;A61P1/16;A61P3/10;A61P7/02;A61P9/00;A61P9/10;A61P11/00;A61P11/02;A61P11/06;A61P17/00;A61P17/06;A61P19/02;A61P21/00;A61P25/00;A61P25/28;A61P27/02;A61P29/00;A61P31/04;A61P31/12;A61P35/00;A61P35/04;A61P37/08;A61P43/00;C07D211/56;C07D211/76;C07D401/06;C07D401/12;C07D401/14;C07D405/12;C07D409/12;C07D409/14;C07D413/12;C07D413/14;C07D417/06;C07D417/12;C07D417/14;C07D471/04;C07D471/08;C07D471/18;C07D491/08;C07D495/04;C07D513/04 |
主分类号 |
C07D487/08 |
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