发明名称 |
Transdermal and topical administration of antihypertensive agents using basic enhancers |
摘要 |
Methods are provided for enhancing the permeability of skin or mucosal tissue to topical or transdermal application of antihypertensive agents. The methods entail the use of a base in order to increase the flux of the agent through a body surface while minimizing the likelihood of skin damage, irritation or sensitization. The permeation enhancer can be an inorganic or organic base. Compositions and transdermal systems are also described.
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申请公布号 |
US2002192301(A1) |
申请公布日期 |
2002.12.19 |
申请号 |
US20020175682 |
申请日期 |
2002.06.19 |
申请人 |
LUO ERIC C.;JACOBSON ERIC C.;HSU TSUNG-MIN |
发明人 |
LUO ERIC C.;JACOBSON ERIC C.;HSU TSUNG-MIN |
分类号 |
A61K8/02;A61K8/19;A61K8/34;A61K8/41;A61K8/92;A61K9/06;A61K9/70;A61K31/04;A61K31/137;A61K31/19;A61K31/20;A61K31/343;A61K31/365;A61K31/4745;A61K31/513;A61K31/60;A61K31/662;A61K31/7004;A61K31/7056;A61K31/737;A61K31/795;A61K38/21;A61K47/02;A61K47/18;A61K47/22;A61Q19/02;(IPC1-7):A61K33/02;A61K33/00 |
主分类号 |
A61K8/02 |
代理机构 |
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代理人 |
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地址 |
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