发明名称 |
Method and system for predicting the biological activity, including toxicology and toxicity, of substances |
摘要 |
A method for assessing toxicity and toxicology of a substance is disclosed comprising: exposing a set of at least two genes to the substance; monitoring the response of each gene in the set of genes to the substance; analyzing the variance of the response to the substance for each gene using contrast analysis; constructing a summary score for each gene in the set of genes; performing a logistic regression analysis upon the summary scores; and using the results of the logistic regression analysis to provide a predictive model regarding the toxicity and toxicology of the substance.
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申请公布号 |
US2002192671(A1) |
申请公布日期 |
2002.12.19 |
申请号 |
US20020052547 |
申请日期 |
2002.01.23 |
申请人 |
CASTLE ARTHUR L.;ELASHOFF MICHAEL |
发明人 |
CASTLE ARTHUR L.;ELASHOFF MICHAEL |
分类号 |
C12Q1/68;G01N33/48;G01N33/50;G01N33/53;G06F19/20;(IPC1-7):C12Q1/68;G06F19/00 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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