The present invention relates to an apparatus for intradermally administering a pharmaceutical composition or other substance through the skin into a mammalian body in a manner that avoids or eliminates excess pain and discomfort normally caused as a result of the microabraders or microneedles entering the epithelial layers beneath the stratum corneum. In a preferred embodiment, the apparatus is a microdevice with an array of microabraders or microneedles with a manipulating member.
申请公布号
WO02100476(A2)
申请公布日期
2002.12.19
申请号
WO2002US18024
申请日期
2002.06.07
申请人
BECTON, DICKINSON AND COMPANY;MARTIN, FRANK, E.;EVANS, JOHN, D.