摘要 |
PROBLEM TO BE SOLVED: To provide a new method of producing (S)-1-(4-phenoxyphenoxy)-2- propanol of high optical purity easily in an industrial scale, being useful as an important synthetic intermediate for (S)-4-phenoxypenyl 2-(2-pyridyloxy)propyl ether. SOLUTION: An ester compound represented by general formula 1 (wherein R<1> is a halogen atom, nitro group, or a 1-4C alkyl; R<2> is a 1-4C alkyl or phenyl which may be substituted) is allowed to react with 4-phenoxyphenol in the presence of base to produce (S)-1-(4-phenoxyphenoxy)-2-propanol. |