发明名称 |
Regulation of cytokine production in a hematopoietic cell |
摘要 |
A method useful for regulating cytokine production by a hematopoietic cell by regulating an MEKK/JNKK-contingent signal transduction pathway in such a cell is disclosed. Methods of identifying compounds capable of specifically regulating an MEKK/JNKK-contingent signal transduction pathway in hematopoietic cells, a kit for identifying cytokine regulators, methods to treat diseases involving cytokine production, and cells useful in such methods are also set forth.
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申请公布号 |
US6495331(B1) |
申请公布日期 |
2002.12.17 |
申请号 |
US19990305720 |
申请日期 |
1999.05.05 |
申请人 |
NATIONAL JEWISH CENTER FOR IMMUNOLOGY AND RESPIRATORY MEDICINE |
发明人 |
GELFAND ERWIN W.;JOHNSON GARY L. |
分类号 |
A61K31/352;C07K14/47;C07K16/40;C12N5/0787;C12N15/85;G01N33/68;(IPC1-7):G01N33/53;A61K45/00;A01N37/18 |
主分类号 |
A61K31/352 |
代理机构 |
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