发明名称 Morphogen-enhanced survival and repair of neural cells
摘要 Disclosed are therapeutic treatment methods, compositions and devices for maintaining neural pathways in a mammal, including enhancing survival of neurons at risk of dying, inducing cellular repair of damaged neurons and neural pathways, and stimulating neurons to maintain their differentiated phenotype. In one embodiment, the invention provides means for stimulating CAM expression in neurons. The invention also provides means for evaluating the status of nerve tissue, including means for detecting and monitoring neuropathies in a mammal. The methods, devices and compositions include a morphogen or morphogen-stimulating agent provided to the mammal in a therapeutically effective concentration.
申请公布号 US6495513(B1) 申请公布日期 2002.12.17
申请号 US19950456033 申请日期 1995.05.31
申请人 CURIS, INC. 发明人 RUEGER DAVID C.;KUBERASAMPATH THANGAVEL;OPPERMANN HERMANN;OZKAYNAK ENGIN;PANG ROY H. L.;COHEN CHARLES M.
分类号 A01N1/02;A61F2/00;A61K6/00;A61K38/17;A61K38/18;A61L27/22;A61L27/24;C07K14/495;C07K14/51;C07K16/22;(IPC1-7):A61K38/00;A61K38/28 主分类号 A01N1/02
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