| 发明名称 |
Induction of a Th1-like response in vitro |
| 摘要 |
The invention provides compositions and methods for stimulating a Th1-like response in vitro. Compositions include fusion proteins and conjugates that contain at least a portion of a heat shock protein. A Th1-like response can be elicited by contacting in vitro a cell sample containing naive lymphocytes with a fusion protein or conjugate of the invention. The Th1-like response can be detected by measuring IFN-gamma produced by the cell sample.
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| 申请公布号 |
US6495347(B1) |
申请公布日期 |
2002.12.17 |
| 申请号 |
US20000613303 |
申请日期 |
2000.07.10 |
| 申请人 |
STRESSGEN BIOTECHNOLOGIES CORPORATION |
发明人 |
SIEGEL MARVIN;CHU N. RANDALL;MIZZEN LEE A. |
| 分类号 |
A61K38/00;A61P37/02;A61P43/00;C07K14/025;C07K14/35;C07K19/00;C12N15/09;C12P21/04;C12Q1/02;G01N33/15;G01N33/50;(IPC1-7):C12P21/04;A61K39/00 |
主分类号 |
A61K38/00 |
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