LIMKs AS MODIFIERS OF THE p53 PATHWAY AND METHODS OF USE
摘要
Human LIMK genes are identified as modulators of the p53 pathway, and thus are therapeutic targets for disorders associated with defective p53 function. Methods for identifying modulators of p53, comprising screening for agents that modulate the activity of LIMK
申请公布号
WO02099048(A2)
申请公布日期
2002.12.12
申请号
WO2002US17423
申请日期
2002.06.03
申请人
EXELIXIS, INC.;FRIEDMAN, LORI;PLOWMAN, GREGORY, D.;BELVIN, MARCIA;FRANCIS-LANG, HELEN;LI, DANXI;FUNKE, ROEL, P.
发明人
FRIEDMAN, LORI;PLOWMAN, GREGORY, D.;BELVIN, MARCIA;FRANCIS-LANG, HELEN;LI, DANXI;FUNKE, ROEL, P.