摘要 |
<p>The invention concerns compounds of general formula (I), wherein, in particular: W represents H, SO2R5, CO(CH2)nR5, (CH2)nR6, CS(CH2)nR5; X represents S or NH; Y represents (CH2)p, CO, (CH2)pCO, CH=CH-CO; Z represents a heterocycle, imidazole, benzimidazole, isoxazole, tetrazole, oxadiazole, thiadazole, pyridine, quinazoline, quinoxaline, quinoline, thiophene; R1 represents COOR6, CONR6R7, CO-NH-CH(R6)-COOR7, CH2NR6R7, CH2OR6, (CH2)pR6, CH=CHR6; R2 represents in particular hydrogen, C1-C10 alkyl, a substituted or unsubstituted phenyl; R3 and R4 represent hydrogen, C1-C6 alkyl; R5 represents a substituted or unsubstituted phenyl or naphthyl; R6 and R7, identical or different, represent hydrogen, C1-C15 alkyl, a heterocycle, an aryl; n represents 0 to 10; p represents 1 to 6.</p> |