A construct comprising a translocation protein linked to a nucleic acid, which encodes an antigen capable of generating a protective immune response in an animal to which it is administered. Such constructs are particularly useful in the formulation of naked DNA vaccines which use plasmid DNA. Various routes for preparing these constructs are described.
申请公布号
WO02098909(A1)
申请公布日期
2002.12.12
申请号
WO2002GB02526
申请日期
2002.05.31
申请人
THE SECRETARY OF STATE FOR DEFENCE;BENNETT, ALICE, MARIE;PERKINS, STUART, DAVID