| 发明名称 |
HYDROXY ALKYL AMINE DERIVATIVES AS BETA-SECRETASE HYDROXY ALKYL AMINE DERIVATIVES AS BETA-SECRETASE INHIBITORSAND THEIR USE FOR THE TREATMENT OF ALZHEINHIBITORS AND THEIR USE FOR THE TREATMENT OF ALZHEIMER'S DISEASE AND SIMILAR DISEASES IMER'S DISEASE AND SIMILAR DISEASES |
| 摘要 |
Disclosed are compounds of formula X, where Rn, R20, R1, R2, R3, and Rc are defined herein. These compounds are useful in treating Alzheimer's disease a nd other similar diseases. Pharmaceutical compositions comprising compounds of formula X and methods of preparing the compounds of formula X are also disclosed.
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| 申请公布号 |
CA2448834(A1) |
申请公布日期 |
2002.12.12 |
| 申请号 |
CA20022448834 |
申请日期 |
2002.05.31 |
| 申请人 |
ELAN PHARMACEUTICALS, INC.;PHARMACIA & UPJOHN COMPANY |
发明人 |
FANG, LARRY;BROWN, DAVID L.;FRESKOS, JOHN N.;VARGHESE, JOHN;ROMERO, ARTHUR GLENN;FOBIAN, YVETTE M. |
| 分类号 |
C07D295/18;A61K31/165;A61K31/166;A61K31/17;A61K31/18;A61K31/192;A61K31/215;A61K31/235;A61K31/265;A61K31/27;A61K31/277;A61K31/341;A61K31/351;A61K31/357;A61K31/381;A61K31/40;A61K31/4015;A61K31/404;A61K31/415;A61K31/4164;A61K31/4166;A61K31/42;A61K31/425;A61K31/426;A61K31/44;A61K31/4406;A61K31/4409;A61K31/445;A61K31/4453;A61K31/4465;A61K31/4965;A61K31/50;A61P25/16;A61P25/28;A61P43/00;C07B51/00;C07C237/12;C07C271/22;C07C275/16;C07C317/44;C07C317/46;C07C317/48;C07C317/50;C07C323/60;C07C325/02;C07C327/32;C07D207/12;C07D207/24;C07D207/26;C07D207/28;C07D209/08;C07D211/46;C07D211/62;C07D211/96;C07D213/30;C07D213/81;C07D213/82;C07D231/12;C07D231/14;C07D233/54;C07D233/64;C07D233/72;C07D233/74;C07D233/90;C07D237/04;C07D237/24;C07D241/24;C07D261/18;C07D277/20;C07D277/36;C07D277/54;C07D277/56;C07D295/185;C07D295/20;C07D307/20;C07D309/12;C07D317/30;C07D319/06;C07D333/32;C07D333/34;C07D333/48;C07D521/00;(IPC1-7):C07C317/26;C07D309/10;C07D211/16;C07C271/18;A61K31/325;A61K31/33;C07C323/39 |
主分类号 |
C07D295/18 |
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