| 发明名称 |
COMBINATION COMPRISING A P-GP INHIBITOR AND AN ANTI-EPILEPTIC DRUG |
| 摘要 |
The invention relates to a combination which comprises a P-glycoprotein (P-gp) inhibitor and an antiepileptic drug selected from phenytoin (5,5-diphenyl-2,4-imidazolidinedione), carbamazepine, lamotrigine, gabapentin, oxcarbazepin, valproic acid, and topiramate, and its use for the prevention, delay of progression or treatment of diseases, in particular epilepsy, especially epilepsy which is resistant to antiepileptic drugs. |
| 申请公布号 |
WO02098418(A1) |
申请公布日期 |
2002.12.12 |
| 申请号 |
WO2002EP06140 |
申请日期 |
2002.06.04 |
| 申请人 |
NOVARTIS AG;NOVARTIS-ERFINDUNGEN VERWALTUNGSGESELLSCHAFT M.B.H.;LOESCHER, WOLFGANG;POTSCHKA, HEIDRUN;SCHMUTZ, MARKUS |
发明人 |
LOESCHER, WOLFGANG;POTSCHKA, HEIDRUN;SCHMUTZ, MARKUS |
| 分类号 |
A61K45/00;A61K31/19;A61K31/197;A61K31/4152;A61K31/4166;A61K31/53;A61K31/55;A61K31/70;A61K38/00;A61K38/13;A61K45/06;A61P25/04;A61P25/06;A61P25/08;A61P25/18;A61P25/20;A61P25/22;A61P25/24;A61P43/00 |
主分类号 |
A61K45/00 |
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