发明名称 |
PROCESS FOR PREPARING CHIRAL DIOL SULFONES AND DIHYDROXY ACID HMG COA REDUCTASE INHIBITORS |
摘要 |
A process is provided for preparing chiral diol sulfones of the structure (I ) where R3 is preferably (II) or (III) where R4a is preferably aryl such as phenyl, and R1a is preferably alkyl such as t-butyl, which are intermediates used in preparing HMG CoA reductase inhibitors.
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申请公布号 |
CA2449813(A1) |
申请公布日期 |
2002.12.12 |
申请号 |
CA20022449813 |
申请日期 |
2002.05.30 |
申请人 |
BRISTOL-MYERS SQUIBB COMPANY |
发明人 |
BRODFUEHRER, PAUL R.;SATTELBERG, THOMAS R., SR.;QIAN, XINHUA;KANT, JOYDEEP |
分类号 |
C07D239/26;A61K31/435;A61K31/4353;A61P3/06;A61P43/00;C07B53/00;C07C67/283;C07C69/30;C07D207/34;C07D213/55;C07D221/16;C07D309/30;C07D319/06;C07D405/06;C07D405/12;C07D413/12;C07D417/12;C07D491/04;C07D491/044;(IPC1-7):C07D221/06;C07D409/02;C07D487/04;C07D495/04;C07D313/10;C07D337/10 |
主分类号 |
C07D239/26 |
代理机构 |
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