An effervescent formulation comprising a low-melting non-steroidal anti-inflammatory drug (NSAID) and an effervescent couple comprising: (a) a granular composition comprising a plurality of solidified melt granules of the (NSAID) with either an acidic or a basic component of the effervescent couple uniformly dispersed therein; and (b) an extra-granular composition comprising the other of the basic or acidic component of the effervescent couple.
申请公布号
WO02098388(A2)
申请公布日期
2002.12.12
申请号
WO2002GB02491
申请日期
2002.05.28
申请人
THE BOOTS COMPANY PLC;HEWITT, PHILIP, THOMAS;SHERRY, ROBERT, ARTHUR;BOOT, JACQUELINE, MARIE
发明人
HEWITT, PHILIP, THOMAS;SHERRY, ROBERT, ARTHUR;BOOT, JACQUELINE, MARIE