TBC1D1S AS MODIFIERS OF THE P53 PATHWAY AND METHODS OF USE
摘要
Human TBC1D1 genes are identified as modulators of the p53 pathway, and thus are therapeutic targets for disorders associated with defective p53 function. Methods for identifying modulators of p53, comprising screening for agents that modulate the activity of TBC1D1 are provided.
申请公布号
WO02099049(A2)
申请公布日期
2002.12.12
申请号
WO2002US17424
申请日期
2002.06.03
申请人
EXELIXIS, INC.;FRIEDMAN, LORI;PLOWMAN, GREGORY, D.;BELVIN, MARCIA;FRANCIS-LANG, HELEN;LI, DANXI;FUNKE, ROEL, P.
发明人
FRIEDMAN, LORI;PLOWMAN, GREGORY, D.;BELVIN, MARCIA;FRANCIS-LANG, HELEN;LI, DANXI;FUNKE, ROEL, P.
