发明名称 |
Humanized immunoglobulin reactive with B7 molecules and methods of treatment therewith. |
摘要 |
The invention relates to a humanized anti-B7-2 antibody that comprises a variable region of nonhuman origin and at least a portion of an immunoglobulin of human origin. The invention also pertains to methods of treatment for various autoimmune diseases, transplant rejection, inflammatory disorders and infectious diseases by administering humanized anti-B7-2 and/or anti-B7-1 antibodies. |
申请公布号 |
ZA200106982(B) |
申请公布日期 |
2002.12.11 |
申请号 |
ZA20010006982 |
申请日期 |
2001.08.23 |
申请人 |
GENETICS INSTITUTE, LLC. C. |
发明人 |
MAN SUNG CO;MAXIMILIANO VASQUEZ;BEATRIZ CARRENO;ABBIE CHERYL CELNIKER;MARY COLLINS;SAMUEL GOLDMAN;GARY S GRAY;ANDREA KNIGHT;DENISE O'HARA;BONITA RUP;GEERTRUIDA M VELDMAN;GARVIN WARNER;STUART FRIEDRICH |
分类号 |
A61K39/395;C07K16/28 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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