Reactive solid support and DNA fragment detection tool

摘要

According to the present invention, there is provided a reactive solid support having a porous substrate wherein the porous region has a fine pore diameter of about 2nm to about 1000nm, a porosity of about 10% to about 90% and a thickness of about 0.01 mu m to about 70 mu m, to the surface of which a group of vinyl sulfonyl groups or their reactive precursor groups are fixed by covalent bond via a linking group, respectively. According to the present invention, a probe of a nucleotide derivative or its analog nucleotide such as an oligonucleotide, a polynucleotide, or a peptide nucleic acid can be fixed in high density with high stability on the surface of a solid support having a porosity. <IMAGE>