发明名称 Methods of immobilizing ligands on solid supports
摘要 A method is provided for immobilizing a ligand, e.g., a nucleic acid, on a solid support. The method includes providing a solid support containing an immobilized latent thiol group, activating the thiol group, contacting the activated thiol group with a nucleic acid comprising an acrylamide functional group, and forming a covalent bond between the two groups, thereby immobilizing the nucleic acid to the solid support. Kits containing the solid supports and method of utilizing the solid supports are also provided.
申请公布号 US6492118(B1) 申请公布日期 2002.12.10
申请号 US20000649637 申请日期 2000.08.28
申请人 MATRIX TECHNOLOGIES CORPORATION 发明人 ABRAMS EZRA S.;ZHANG TIANHONG;MIELEWCZYK SLAWOMIR;PATTERSON BRIAN C.
分类号 G01N33/53;B01J20/281;B05D3/00;C07H21/04;C07K5/00;C12M1/00;C12M1/34;C12M1/36;C12N11/16;C12N15/09;C12Q1/68;G01N30/88;G01N33/543;G01N33/547;G01N33/566;(IPC1-7):C12Q1/68 主分类号 G01N33/53
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