发明名称 |
Amorphous form of cell cycle inhibitor having improved solubility and bioavailability |
摘要 |
The present invention provides a method of preparing an amorphous, pharmaceutically active form of a compound of formula Iwhich is substantially free of crystalline compound.
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申请公布号 |
US6492530(B1) |
申请公布日期 |
2002.12.10 |
申请号 |
US20020120460 |
申请日期 |
2002.04.11 |
申请人 |
HOFFMANN-LA ROCHE INC. |
发明人 |
ALBANO ANTONIO A.;PHUAPRADIT WANTANEE;SANDHU HARPREET K.;SHAH NAVNIT HARGOVINDAS |
分类号 |
A61K31/404;A61P35/00;C07D403/14;(IPC1-7):C07D403/14 |
主分类号 |
A61K31/404 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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