FXIII DETECTION FOR VERIFYING SERUM SAMPLE AND SAMPLE SIZE AND FOR DETECTING DILUTION

摘要

Analyses of serum samples for the presence and amount of either of the two
subunits of
human Factor XIII protein are used as a means of eliminating a significant
source of error that
arises in the testing of serum and plasma. For serum samples, a negative
result of an analysis
for the presence of subunit a is a means of verifying that a sample is indeed
serum, while a
negative or positive result for subunit a serves to distinguish serum
(negative) from plasma
(positive). A positive result for the presence of subunit b is a means of
verifying that the
sample is either serum or plasma and not any other biological fluid. A
quantitative analysis of
subunit b is a means of verifying that the sample is of the intended volume
rather than having
been reduced in volume due to improper sampling. A quantitative analysis of
subunit b is also
a means of verifying the dilution of a sample of either serum or plasma.