发明名称 |
NON-NATURAL GALANIN RECEPTOR LIGANDS |
摘要 |
Compounds which are non-natural galanin receptor ligands are disclosed. The ligands are of small size, have agonist or antagonist galanin activity and may cross the blood-brain barrier to displace galanin receptors. The ligands are useful as medicaments for treatment of convulsions (e.g. in epilepsy), diseases and disorders related to endocrinology (e.g., growth hormone, insulin or prolactin release), tumors expressing galanin receptors, feeding disorders pain, allodynia, psychiatric disorders such as depression (involving e.g., noradrenaline or serotonin), cognitive disorders (e.g. Alzeimer's disease), and the like. |
申请公布号 |
WO02096934(A1) |
申请公布日期 |
2002.12.05 |
申请号 |
WO2002SE01002 |
申请日期 |
2002.05.24 |
申请人 |
KEMIA, INC.;LANGEL, UELO;SAAR, KUELLIKI;BARTFAI, TAMAS |
发明人 |
LANGEL, UELO;SAAR, KUELLIKI;BARTFAI, TAMAS |
分类号 |
A61K38/00;A61P25/08;C07K5/065 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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