发明名称 |
PHARMACEUTICAL USE FOR SECRETED BACTERIAL EFFECTOR PROTEINS |
摘要 |
A polypeptide conjugate contains a bacterial injectable effector protein, secreted by a modified pilus or "needle-like" structure comprising a type II I or type IV secretion apparatus, and a carrier that targets the conjugate to a target cell. The effector protein is used for a variety of purposes includin g treatment of neurodegenerative disease, intracellular infection and diseases associated with defects of secretion.
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申请公布号 |
CA2448963(A1) |
申请公布日期 |
2002.12.05 |
申请号 |
CA20022448963 |
申请日期 |
2002.05.21 |
申请人 |
HEALTH PROTECTION AGENCY |
发明人 |
SHONE, CLIFFORD CHARLES;SUTTON, JOHN MARK |
分类号 |
C12N15/09;A61K31/711;A61K35/74;A61K38/00;A61K47/48;A61K48/00;A61P11/00;A61P11/06;A61P21/00;A61P25/00;A61P25/28;A61P31/00;A61P43/00;C07K14/33;C07K14/34;C07K19/00;(IPC1-7):C12N15/31;A61K31/708;A61K38/16;A61K39/02;A61K47/42;C07K14/195;C07K14/24;C07K14/255;C07K17/00;C12N15/62 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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