发明名称 |
CRIPTO TUMOUR POLYPEPTIDE |
摘要 |
Compositions and methods for the therapy and diagnosis of cancer, particularly lung, colon, colorectal and breast cancer, are disclosed. Illustrative compositions comprise one or more Cripto tumor polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases, particularly lung, colon, colorectal and breast cancer. |
申请公布号 |
WO0216413(A3) |
申请公布日期 |
2002.12.05 |
申请号 |
WO2001EP09646 |
申请日期 |
2001.08.20 |
申请人 |
SMITHKLINE BEECHAM BIOLOGICALS S.A.;CASSART, JEAN-POL;COCHE, THIERRY;PALMANTIER, REMI, M.;VINALS Y DE BASSOLS, CARLOTA |
发明人 |
CASSART, JEAN-POL;COCHE, THIERRY;PALMANTIER, REMI, M.;VINALS Y DE BASSOLS, CARLOTA |
分类号 |
C12N15/09;A61K35/26;A61K38/00;A61K39/00;A61K48/00;A61P35/00;A61P37/04;A61P43/00;C07K14/475;C07K14/82;C07K19/00;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/12 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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