TUMOR TARGETING WATER SOLUBLE PORPHYRIN DERIVATIVES, AND PREPARATION METHOD AND USE THEREOF

摘要

PURPOSE: Provided are tumor targeting water soluble porphyrin derivatives which form a complex with other anticancer agents and are thus used for delivering the anticancer agents to tumor tissues, and their preparation method and use, thereby minimizing an ill effect of an anticancer agent and increasing water-solubility. CONSTITUTION: The porphyrin derivative is represented by the formula(2), wherein m is zinc or two of hydrogen ions; Y is 0 or RX; R is selected from alkyl amine or alkylcarboxylate; and X is a halide ion.