Process for reducing alpha-amino ketones

摘要

The present invention has its objects to provide a method for reducing alpha -aminoketone derivatives under mild conditions with high stereoselectivity. This invention is a method for reducing alpha -aminoketone which comprises reacting an alpha -aminoketone derivative of general formula (1) with a compound prepared from an organoaluminum compound of general formula (4), a sulfonic acid derivative of general formula (5), and an alcohol compound of general formula (6) to give an alpha -aminoalcohol derivative of general formula (7).