发明名称 |
METHOD OF OBTAINING P-CHIRAL ANALOQUES OF NUCLEOTIDES |
摘要 |
The process of the instant invention is drawn to the synthesis of modified P-chiral nucleotide analogues in the form of pure diastereomers possessing preselected configuration at the P-atom. Oligonucleotides prepared by the method of the invention containing P-chiral compounds have enhanced hybridization and transporting properties. |
申请公布号 |
PL184612(B1) |
申请公布日期 |
2002.11.29 |
申请号 |
PL19970319677 |
申请日期 |
1997.04.25 |
申请人 |
PAN,CENTRUM BADAN MOLEKULARNYCH I MAKROMOLEKULARNYCH |
发明人 |
STEC WOJCIECH J.;WOZNIAK LUCYNA A.;CHWOROS ARKADIUSZ;PYZOWSKI JAROSLAW |
分类号 |
C07H21/00 |
主分类号 |
C07H21/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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