| 发明名称 |
A NOVEL CRYSTALLINE FORM OF N-[4-[2- (2-AMINO-4, 7-DIHYDRO- 4-OXO -3H-PYRROLO [2, 3-D] PYRIMIDIN -5-YL) ETHYL]BENZOYL] -L-GLUTAMIC ACID AND PROCESS THEREFOR. |
| 摘要 |
<p>The invention relates to the field of pharmaceutical and organic chemistry and provides an improved process for preparing the novel heptahydrate crystalline salt of multitargeted antifolate N-[4- [2-(2-amino -4, 7-dihydro -4-oxo -3H-pyrrolo [2, 3-d] -pyrimidin-5 -yl) ethyl] benzoyl] -L-glutamic acid.</p> |
| 申请公布号 |
MXPA02008242(A) |
申请公布日期 |
2002.11.29 |
| 申请号 |
MX2002PA08242 |
申请日期 |
2001.02.12 |
| 申请人 |
ELI LILLY AND COMPANY |
发明人 |
REUTZEL-EDENS, SUSAN, MARIE |
| 分类号 |
A61K9/08;A61K31/519;A61P35/00;C07D487/04;(IPC1-7):A61K31/519;C07D239/00;C07D209/00 |
主分类号 |
A61K9/08 |
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