DNA MOLECULE WITH INSULATING ACTIVITY AGAINST CHROMOSOMAL POSITION EFFECTS IN GENE TRANSFER PROCESSES IN ANIMAL CELLS
摘要
The invention relates to a DNA molecule or a fragment of said DNA molecule obtained from the LCR (Locus Control Region) sequence of the mouse tyrosinase gene. Said sequence has insulating activity against chromosomal position effects in gene transfer processes in animal cells. The DNA molecule can be used to introduce transgenes and to reduce the variability of the transgene expression in animal cells.
申请公布号
WO02095031(A1)
申请公布日期
2002.11.28
申请号
WO2002ES00221
申请日期
2002.05.10
申请人
CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS;MONTOLIU JOSE, LLUIS;GIRALDO CARBAJO, PATRICIA;BUSTURIA JIMENO, ANA, MARIA, DE
发明人
MONTOLIU JOSE, LLUIS;GIRALDO CARBAJO, PATRICIA;BUSTURIA JIMENO, ANA, MARIA, DE
