HIGH THROUGHPUT SCREENING FOR INHIBITORS OF FATTY ACID, ERGOSTEROL, SPHINGOLIPID, OR PHOSPHOLIPID SYNTHESIS IN FUNGI

摘要

Methods for identifying compounds that are inhibitors of fatty acid, ergosterol, sphingolipid, or phospholipid synthesis are disclosed. Such compounds can be derivatized to produce antifungal agents, which can be used in methods of treating fungal infections (e.g., in humans, animals, and plants). The disclosed methods allow for high throughput screening of libraries of test compounds.