HYPOXIA INDUCIBLE FACTORS AND USES THEREOF FOR INDUCING ANGIOGENESIS AND IMPROVING MUSCULAR FUNCTIONS

摘要

This invention provides HIF-3.alpha. nucleic acid and sequences. Also provid ed are methods for using HIF-3.alpha. nucleis acids, proteins, fragments, antibodies probes, and cells, to characterize HIF-3.alpha., modulate HIF- 3.alpha. cellular levels, induce angiogenesis, improve muscular functions, a nd treat coronary and cardiac diseases in mammals.