发明名称 Solid phase synthesis
摘要 The present invention relates to a support system for solid phase synthesis of oligomers, such as oligonucleotides, wherein the starting compound is bound to the support via a disiloxyl linkage. Furthermore, the invention relates to a method for synthesis of oligonucleotides on a solid support. The support system comprises a stable disiloxyl linkage providing high nucleoside loadings to the support and the method allows convenient non-laborious oligomer synthesis.
申请公布号 US2002177698(A1) 申请公布日期 2002.11.28
申请号 US20020106832 申请日期 2002.03.25
申请人 QUIATECH AB 发明人 KWIATKOWSKI MAREK;NILSSON MATS;LANDEGREN ULF
分类号 C12P19/34;C07H21/00;C07H21/02;C07H21/04;C07H23/00;(IPC1-7):C07H21/04;C08G63/91 主分类号 C12P19/34
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