METHODS OF TREATING INFLAMMATION, PARTICULARLY DIABETES

摘要

A method of treating inflammation and/or diabetes in a mammal involves administering to the mammal an effective anti-inflammatory amount of allogeneic lymphocytic T cells. Among useful cells are TALL-104 cells, ATCC Accession No. CRL 11386, which cells have been modified by stimulation in vitro by treatment with a cytokine and gamma irradiation at a dose suitable to irreversibly arrest cell proliferation. These modified cells are characterized by irreversibly arrested cell proliferation and non-MHC restricted cytotoxic activity. Among other useful cells are TALL-106 cells.