发明名称 |
PRODUCTION OF SECONDARY METABOLITES |
摘要 |
A method of producing a secondary metabolite includes providing an elongate porous substrate with a biofilm of micro-organism and which is arranged with one end of the substrate being at a higher elevation than the other end of the substrate so that the substrate is at an angle to the horizontal. A nutrient solution flows through the substrate, at a rate which is sufficiently low for a nutrient gradient to be established across the biofilm such that the nutrient concentration at a high level along the gradient is sufficiently high to support primary growth of the micro-organism, and the nutrient concentration at a low level along the gradient is sufficiently low to induce secondary growth of the micro-organism. The substrate's angle with the horizontal ensures that any droplets of nutrient permeate forming on the biofilm run towards the lower end of the substrate. |
申请公布号 |
WO02094979(A2) |
申请公布日期 |
2002.11.28 |
申请号 |
WO2002IB01686 |
申请日期 |
2002.05.17 |
申请人 |
LEUKES, WINSTON, DANIEL;GARCIN, CLIVE |
发明人 |
LEUKES, WINSTON, DANIEL;GARCIN, CLIVE |
分类号 |
C12M1/12;C12M1/14;C12M1/40 |
主分类号 |
C12M1/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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