发明名称 |
PHARMACEUTICAL COMPOSITION FOR USE IN HORMONE REPLACEMENT THERAPY |
摘要 |
One aspect of the invention is concerned with a method of hormone replacement therapy, which method comprises administering to a person in need of such a therapy an effective amount of an estrogenic component selected from the group consisting of: substances represented by the formula (I) in which formula R1, R2, R3, R4 independently are a hydrogen atom, a hydroxyl group or an alokxy group with 1-5 carbon atoms; each of R5, R6, R7 is a hydroxyl group; and no more than 3 of R1, R2, R3, R4 are hydrogen atoms; precursors capable of liberating a substance according to the aforementioned formula when used in the present method, and mixtures thereof; said composition containing virtually no progestogen or anti-progestin. Another aspect of the invention relates to a drug delivery system for enteral or parenteral administration that contains at least 1 mu g of the aforementioned estrogenic component and virtually no progestogen or anti-progestin.
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申请公布号 |
WO02094276(A1) |
申请公布日期 |
2002.11.28 |
申请号 |
WO2002NL00317 |
申请日期 |
2002.05.17 |
申请人 |
PANTARHEI BIOSCIENCE B.V.;HOLINKA, CHRISTIAN, FRANZ;COELINGH BENNINK, HERMAN, JAN, TIJMEN;BUNSCHOTEN, EVERT, JOHANNES |
发明人 |
HOLINKA, CHRISTIAN, FRANZ;COELINGH BENNINK, HERMAN, JAN, TIJMEN;BUNSCHOTEN, EVERT, JOHANNES |
分类号 |
A61K9/00;A61K31/00;A61K31/56;A61K31/565;A61K45/06;A61P5/30;(IPC1-7):A61K31/565 |
主分类号 |
A61K9/00 |
代理机构 |
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代理人 |
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地址 |
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