ENGINEERED SECRETED ALKALINE PHOSPHATASE (SEAP) REPORTER GENES AND POLYPEPTIDES

摘要

The invention provides a novel reporter gene (mSEAP) capable of being expressed in a mammal for extended periods of time. Nucleic acids encoding t he reporter gene, cells and vectors comprising the nucleic acids, and methods o f using the reporter gene to identify expression vectors and screen for drug compounds in an animal are also disclosed.