发明名称 |
METHODS AND COMPOUNDS FOR THE DIAGNOSIS OF INFLAMMATORY DISEASE AND IDENTIFICATION OF PHARMACOLOGICAL AGENTS |
摘要 |
Methods for the diagnosis of inflammatory bowel diseases and the identification of agents useful in the treatment of such diseases based upon the agent's effect on reducing Pim-2 expression. Figure 6 shows that Pim-2 i s required for TNF-alpha-induced IL-6 expression in HeLa cells.
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申请公布号 |
CA2448265(A1) |
申请公布日期 |
2002.11.28 |
申请号 |
CA20022448265 |
申请日期 |
2002.05.23 |
申请人 |
BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. |
发明人 |
LI, JUN;BARTON, RANDALL;LI, XIANG JOHN |
分类号 |
A61K38/00;C12Q1/48;G01N33/68;(IPC1-7):C12Q1/68;C12N5/10;C12N9/12;C12P19/34;G01N33/53;A61K31/70 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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