摘要 |
PROBLEM TO BE SOLVED: To obtain a preparation having safety, extremely good in the stability of the preparation and excellent in transdermal absorption of the active ingredient. SOLUTION: The preparation is obtained by subjecting an oil-soluble active ingredient, an oil component, a polyhydric alcohol and a surfactant to a high- pressure emulsifying treatment followed by mixing and stirring the obtained emulsion with water and a water-soluble component.
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