Multi-layered pharmaceutical composition for both intraoral and oral administration

摘要

New pharmaceutical composition in unit dosage form 1 are disclosed for both intraoral and oral administration to a mammalian patient, said unit dosage form configured to be placed intraorally of said patient, which comprises: (a) as a first portion 3 , at least one discrete outer layer comprising a therapeutically effective amount of at least one pharmaceutically active ingredient capable of intraoral administration; and (b) as a second portion 4 located within said first portion 3, a therapeutically effective amount of at least one pharmaceutically active ingredient capable of oral administration and which is releasable and orally ingestible by the patient after the outer layer has disintegrated or has dissolved intraorally. <IMAGE>