发明名称 |
NOVEL PROTEIN AND GENE ENCODING THE SAME |
摘要 |
<p>A novel mechanosensitive channel protein derived from mouse or humans which is expressed specifically in the kidney and has the function of non-selectively transporting cation into cells in response to a mechanical stimulus; a DNA encoding these proteins; a method of screening cation channel activity activators or inhibitors with these proteins; and antibodies to these proteins. The above-described proteins are useful as a diagnostic agent or a therapeutic agent for diseases based on abnormalities in the cation channel, such as hypertension or diabetes, or as a tool for screening chemicals for preventing and/or treating these diseases.</p> |
申请公布号 |
EP1260585(A1) |
申请公布日期 |
2002.11.27 |
申请号 |
EP20010906253 |
申请日期 |
2001.02.23 |
申请人 |
DAIICHI PHARMACEUTICAL CO., LTD. |
发明人 |
SUZUKI, MAKOTO;ISHIBASHI, KEN'ICHI |
分类号 |
A61K38/00;C07K14/47;C07K14/705;C07K16/18;C12N15/12;G01N33/68;(IPC1-7):C12N15/12 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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