发明名称 |
THERAPEUTIC USE OF RANK ANTAGONISTS |
摘要 |
Provided herein are methods of treating various medical conditions that require the formation of new bone by administering an effective amount of a RANK antagonist. Antagonists suitable for use in the subject methods include soluble RANK polypeptides that bind RANKL, antisense oligonucleotides that inhibit RANK activity, antibodies specific for RANK or RANKL and osteoprotegerin.
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申请公布号 |
CA2447518(A1) |
申请公布日期 |
2002.11.21 |
申请号 |
CA20022447518 |
申请日期 |
2002.05.17 |
申请人 |
IMMUNEX CORPORATION |
发明人 |
DOUGALL, WILLIAM C.;ANDERSON, DIRK M. |
分类号 |
A61K45/00;A61K31/7088;A61K38/00;A61K38/17;A61K39/395;A61K48/00;A61P1/02;A61P5/20;A61P7/00;A61P7/06;A61P19/00;A61P19/02;A61P31/04;A61P35/00;A61P41/00;A61P43/00;C07K14/47;C07K14/705;C07K16/18;C07K16/28;(IPC1-7):A61K38/00;A61K39/00;C07K14/00;C07H21/02;C07H21/04;G01N33/53 |
主分类号 |
A61K45/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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