| 摘要 |
<p>The present invention relates to an effective and practical method for preparing retinol (Chemical Formula 2), retinal (Chemical Formula 3) and βcarotene (Chemical Formula 4) by using C-15 allylic disulfone compound (Chemical Formula 1) as an intermediate compound, that is prepared through a stable and economic process, for syntheses of retinoid and carotenoid compounds.According to the present invention, retinol (Chemical Formula 2), retinal (Chemical Formula 3) and β-carotene (Chemical Formula 4) are effectively prepared, via coupling reaction of carbanion that is obtained from deprotonation of the C-15 disulfone compound (Chemical Formula 1) by excess amount (2 equivalents or more) of base, with C-5 halo-acetate compound (A), C-5 halo-acetal compound (C) and C-10 dihaloallylic sulfide compound (F), respectively followed by dehydrosulfonation reaction.</p> |
