发明名称 |
Oligomerized receptors which affect pathways regulated by transmembrane ligands for elk-related receptor tyrosine kinases |
摘要 |
A method of modulating the biological activity of a transmembrane ligand for an Elk-related receptor tyrosine kinase in a cell expressing the transmembrane ligand, comprising forming a complex between a purified and isolated oligomerized Elk-related receptor tyrosine kinase, or an isoform or an extracellular domain of the kinase, and a transmembrane ligand expressed on the cell, thereby affecting a pathway in the cell which is regulated by the transmembrane ligand.
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申请公布号 |
US2002172984(A1) |
申请公布日期 |
2002.11.21 |
申请号 |
US20020138787 |
申请日期 |
2002.05.03 |
申请人 |
MOUNT SINAI HOSPITAL CORPORATION |
发明人 |
HOLLAND SACHA;MBAMALU GERALDINE;PAWSON TONY |
分类号 |
A61K38/00;C07K14/47;C07K14/705;C12N9/12;C12N15/12;C12Q1/68;(IPC1-7):G01N33/567;A61K38/51 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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