| 发明名称 |
Chimeric IL-10 proteins and uses thereof |
| 摘要 |
Disclosed are chimeric proteins having IL-10 fused to an enzymatically inactive polypeptide which increases the circulating half-life of IL-10. The chimeric polypeptides are useful for treating or preventing septic shock, inhibiting the development of Type I diabetes, and treating multiple myeloma in a patient.
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| 申请公布号 |
US2002173628(A1) |
申请公布日期 |
2002.11.21 |
| 申请号 |
US20020145481 |
申请日期 |
2002.05.14 |
| 申请人 |
BETH ISRAEL HOSPITAL ASSOCIATION |
发明人 |
STROM TERRY B.;ZHENG XIN XIAO;STEELE ALAN |
| 分类号 |
A61K38/00;C07K14/52;C07K16/46;C12N15/24;C12N15/62;(IPC1-7):A61K38/52;A61K38/20;A61K39/395;C12N9/10 |
主分类号 |
A61K38/00 |
| 代理机构 |
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